HMGB1 Localization during Experimental Periodontitis

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HMGB1 Localization during Experimental Periodontitis

AIM This study sought to investigate the in vitro expression profile of high mobility group box 1 (HMGB1) in murine periodontal ligament fibroblasts (mPDL) stimulated with LPS or IL-1β and in vivo during ligature- or LPS-induced periodontitis in rats. MATERIAL AND METHODS For the in vivo study, 36 rats were divided into experimental and control groups, and biopsies were harvested at 7-30 d fo...

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ژورنال

عنوان ژورنال: Mediators of Inflammation

سال: 2014

ISSN: 0962-9351,1466-1861

DOI: 10.1155/2014/816320